ANTI-AGING REGENERATING CREAM FACE & NECK
Patent-pending technology
  • Concentration and particle size determination by Nanosight.
  • Analysis by Nanosight and Scanning Electron Microscopy (SEM).
  • Antioxidant capacity assay using DPPH (2,2-diphenyl-1-picrylhydrazyl).
  • Ensayos in vitro en fibroblastos dérmicos humanos (HDF).
  • In vivo were conducted realizado en 20 sujetos.

Additional Marketing Claims

  • Paraben-free
  • Cruelty-free
  • Vegan
  • Dermatologically tested fragrance*
  • Powered by functionalized plant exosomes
  • Contains plant-based peptides
  • Formulated with liquid crystal-forming emulsifiers that biomimetically replicate the skin's lipid architecture
  • Sanitary airless packaging prevents oxidation and minimizes contact with air
  • Rich and nourishing cream, non-greasy, quickly absorbed, with a “second skin” effect
*Fragrance evaluated under dermatological criteria.

Description

ANTI-AGING REGENERATING CREAM FACE & NECK This cream is designed to prevent the appearance of visible signs of skin aging. It revitalizes the skin and helps reduce wrinkles and expression lines, providing greater firmness and elasticity to both the face and neck.

It is powered by EXOREVAGE  CICA*, a patent-pending technology based on functionalized plant exosomes derived from Curcuma longa. Centella asiaticaInspired by ancestral botanical traditions and developed through green biotechnology, this technology extracts exosomes from plant stem cell platforms and functionalizes them to enhance their bioactivity and targeted performance. Integrated with the mineral legacy of precious pearl and optimized with biomimetic plant squalane, EXOREVAGE  CICA offers a non-invasive, needle-free approach to advanced skincare.

Unlike conventional plant exosomes, EXOREVAGE  CICA incorporates a structural modification that includes:

  • SqualaneActs as a lipid permeation enhancer, integrated into the exosomal membranes to optimize cellular fusion and promote a more efficient release of bioactives.
  • Ionic Calcium Cofactors:Sourced from precious pearl, these modulate the surface charge of the exosomes, facilitating the formation of coordination complexes with cellular receptors and membranes.

This modification improves selective affinity with skin cells and enhances exosome-cell interaction, establishing an intelligent biomimetic delivery system that promotes cellular regeneration and refines skin texture.

*The registered trademark may not be used without written authorization from PREBEL.

Texture

A rich and nourishing, non-greasy cream with a smooth consistency and rapid absorption. It provides long-lasting hydration, protection, and nourishment, offering an enveloping "second-skin" sensation.

Claims enabled by EXOREVAGE  CICA

  • Up to 2 billion functionalized CICA plant exosomes per mL of product (1).
  • The plant exosomes in EXOREVAGE  CICA are functionalized—modified to offer greater stability and a more uniform structure compared to conventional CICA exosomes (2).
  • Up to 20% higher antioxidant capacity vs. conventional CICA exosomes (3).
  • Up to 72% acceleration of the skin recovery process compared to the basal control, with an effect comparable to dermal growth factors (4).
  • Significant increase in firmness by up to 19% after 56 days and elasticity by up to 8% (5).
  • Comprehensive rejuvenating effect with overall improvement in six parameters:
    • Up to 78% reduction in wrinkles
    • Up to 51% reduction in roughness
    • Up to 65% reduction in pores
    • Up to 30% reduction in spots
    • Up to 63% reduction in red spots (cross-polarized light)
    • Hasta 57% reducción de porfirinas (luz UV) (5)
  • More efficient release of bioactive compounds thanks to the integration of squalane into exosomal membranes.
  • Afinidad selectiva mejorada con células cutáneas objetivo, derivada de la modulación de la carga superficial mediante iones de calcio provenientes de perla preciosa.

Technical Support:

Directions for Use

Application

Place both thumbs on the applicator of the container and press firmly until the system is activated. Then, press the upper pump completely to dispense the cream.

Apply to the face and neck, morning and night.

Images