REGENERATIVE EYEBROW & EYELASH SERUM – INTENSIVE BOOSTER is an advanced formulation designed to increase eyebrow and eyelash density, powered by EXOREVAGE® CURCUMA, a patent-pending functionalized plant-exosome technology derived from Curcuma longa. Rooted in ancestral botanical tradition and evolved through green biotechnology, plant-exosomes are sustainably obtained from stem-cell platforms and functionalized to enhance bioactivity and targeted performance. Integrated by the precious heritage of malachite and boosted with biomimetic vegetable based squalane, EXOREVAGE® CURCUMA delivers a non-invasive, needle-free skinification approach, redefining eyebrow and eyelash care by treating follicles as skincare extensions.

Unlike conventional plant-based exosomes, EXOREVAGE® CURCUMA is a technology of functionalized plant-based exosomes from Curcuma longa modified with squalane as a lipidic permeation booster that integrates in its membranes and optimizes cell fusion in the skin and ionic cofactors of copper coming from precious malachite gemstone which modulate the surface charge of the exosomes, enabling the formation of coordination complexes with cellular receptors and membranes.This modification provides a more effective release of exosome content and selective affinity to enhance the interaction between exosomes and follicle cells. This smart biomimetic delivery system supports cell regeneration, follicle activation, and hair longevity.

• It’s a water-based, transparent formula, non-greasy, enabling easy and clump-free application.
• It has an innovative dual applicator for easier and more accurate application in eyebrows & eyelashes.

TEXTURE: Water-based, gelly and transparent formula that is non-greasy, allowing for easy and clump-free application

PREBEL EXOREVAGE® CURCUMA technology – enabled claims for eyebrow and eyelashes:

• Up to 700 million of functionalized plant exosomes from CURCUMA/mL of product (1)
• The plant-based exosomes in EXOREVAGE® CURCUMA are functionalized, meaning that are more stable and more uniform structure compared to common CURCUMA exosomes (2)
• Up to 67% higher antioxidant capacity compared to common CURCUMA exosomes (3)
• Up to a 177% increase in the induction of proliferation of Human Follicle Dermal Papilla Cells (HFDPC) and greater effect than key growth factors involved in the hair growth cycle like FGF, VEGF, IGF-1 (4)
• Increase of eyelash density by up to 56% after 4 months of daily use 5 and increase of eyebrow density by up to 35% after 4 months of daily use (5)
• More effective release of bioactives: Due to the integration of the squalane as a lipidic permeation booster in the Curcuma longa exosome membranes
• More selective affinity with target follicle cells: Due to the modulated surface charge of Curcuma longa exosomes mediated by the cooper ions from precious malachite gemstone.

1. Supported by tests of determination of particle concentration and size by Nanosight
2. Supported by test of  Nanosight and Scanning Electron Microscopy (SEM)
3. Supporte by test of antixidant capacity with DPPH (2,2-Diphenyl-1-picrylhydrazyl)
4. In vitro tests of induction of Human Follicle Dermal Papilla Cells (HFDPC)
5. In vivo clinical tests performed with 20 subjects

*Trademark cannot be used without written permission from PREBEL.