REGENERATIVE EYEBROW & EYELASH SERUM – INTENSIVE BOOSTER
Patent-pending technology

Description

REGENERATIVE EYEBROW & EYELASH SERUM – INTENSIVE BOOSTER is an advanced formulation designed to increase the density of eyebrows and eyelashes. It is powered by EXOREVAGE  Curcuma*, a patent-pending technology based on functionalized plant exosomes derived from Curcuma longa. Curcuma longa.

Inspired by ancestral botanical traditions and developed through green biotechnology, this technology obtains exosomes from plant stem cell platforms, which are subsequently functionalized to enhance their bioactivity and targeted performance. Integrated with the mineral legacy of malachite and optimized with biomimetic plant-based squalane, EXOREVAGE  Curcuma offers a non-invasive, needle-free approach under the "skinification" concept, redefining eyebrow and eyelash care by treating follicles as extensions of skincare.

Unlike conventional plant exosomes, EXOREVAGE  Curcuma incorporates a structural modification that includes:

  • Squalane, as a lipid permeation enhancer, integrated into the exosomal membranes to optimize cellular fusion and promote a more efficient release of bioactive content.
  • Copper ionic cofactors,derived from malachite, which modulate the surface charge of the exosomes, allowing for the formation of coordination complexes with receptors and cell membranes.

 

This modification provides greater selective affinity with follicular cells and boosts exosome-cell interaction, configuring an intelligent biomimetic delivery system that promotes cellular regeneration, follicular activation, and hair longevity.

It is a transparent, water-based, and non-greasy formula that allows for easy, clump-free application.

It features an innovative dual applicator, designed to facilitate precise application on both eyebrows and eyelashes.

*The registered trademark may not be used without written authorization from PREBEL.

Texture

Transparent, aqueous gel-type formula; non-greasy, allowing for uniform application without buildup.

Claims enabled by EXOREVAGE  Curcuma

  • Up to 700 million functionalized Curcuma plant exosomes per mL of product (1).
  • The plant exosomes in EXOREVAGE  Curcuma are functionalized, meaning they are modified to offer greater stability and a more uniform structure compared to conventional Curcuma exosomes (2).
  • Up to 67% higher antioxidant capacity compared to conventional Curcuma exosomes (3).
  • Up to 177% increase in Human Follicle Dermal Papilla Cell (HFDPC) proliferation, showing a superior effect to key hair cycle factors such as FGF, VEGF, and IGF-1 (4).
  • Eyelash density increase of up to 56% after 4 months of daily use, and eyebrow density increase of up to 35% after 4 months of daily use (5).
  • More efficient release of bioactives thanks to the integration of squalane as a lipid permeation enhancer in the exosomal membranes.
  • Enhanced selective affinity with follicular cells, derived from surface charge modulation via copper ions from malachite.

Technical Support:

  • Concentration and particle size determination by Nanosight.
  • Analysis by Nanosight and Scanning Electron Microscopy (SEM).
  • Antioxidant capacity assay using DPPH (2,2-diphenyl-1-picrylhydrazyl).
  • Ensayo in vitro HFDPC cell proliferation assay.
  • In vivo were conducted on 20 subjects.

Additional Marketing Claims

  • Silicone-free
  • Paraben-free
  • Fragrance-free
  • Cruelty-free
  • Vegan
  • Formulated with peptides and a styling polymer
  • Exclusive dual applicator for more precise application on brows and lashes
  • Increases eyelash density, making them look fuller and more attractive
  • Strengthens the bulb from the root, stimulating regeneration for visibly stronger and longer brows and lashes
  • Enhances the natural beauty of the eyes, providing greater definition
  • Non-greasy, aqueous, and transparent formula for easy application

Directions for Use

Application

For best results, apply to eyebrows and eyelashes morning and night.

Eyelashes: Ensure they are clean and makeup-free. Use the tip of the applicator to slide the serum along the lash line.

Eyebrows: Ensure they are clean and makeup-free. Use the brush body applying in upward motions and comb to distribute evenly.

Images